1. Lifestyle
  2. Health & Wellness

The Bryan Johnson Effect: When Biohacking Meets The Real World

By Rudra Mulmule | LAST UPDATED: MAR 12, 2025
Bryan Johnson; WTF Nikhil Kamath; Air Quality India
Is anti-ageing an unattainable utopia?Getty Images

For a man that has dedicated his life – and millions of dollars – to fine tune his body at a cellular level, Bryan Johnson’s abrupt exit from Nikhil Kamath’s WTF podcast this week was seen by many angry Indians as a sign of weakness.

Despite the N95 mask, 3 air purifiers and a luxurious set up in a 5-star hotel, Johnson cited concerns over air quality (indoor air quality had an AQI of 130 and PM2.5 levels at 75 µg/m³, equivalent to smoking 3.4 cigarettes over 24 hours) leading to another internet moment. But the conversation around air pollution isn’t a trend and will not fade out anytime soon.

In fact, the exit has stirred an interesting debate: Can extreme biohacking withstand the unpredictability of the real world?

In a world of high-performance living, luxury has often been about perfecting the imperfect; providing the finest of the things. Be it a tailored suit, a fine timepiece, or the finest of gems. And the anti-ageing mogul brings this philosophy to the human body itself.

Johnson’s Project Blueprint is a meticulous protocol that intends to redefine health and human existence; a high-end machine with data-driven diet, AI monitored sleep, medical-grade supplements, and strict environmental conditions, all this calibration to slow down ageing.

The relentless pursuit of perfect skin and the erasure of aging feels like a slouching Sphinx in Bethlehem- an eerie harbinger of a future where time itself is defied, yet something unnatural looms.

Know: The Secret To Good Skin Lies In What You Don’t Eat

Johnson’s lifestyle is built on optimization. When asked the degree of damage poor air quality can have on one’s system, he said “the contaminants can wreak havoc” leading to health issues like asthma, lung irritation, and neurological dysfunction.

“It’s a whole-body damage…it gets into tissues, lodges in and is very hard to remove" to the point it's difficult to clean, he continued. While the data out there suggests that contaminated water can be purified, food can be organically grown, limited engineering is available to help us purify air contamination.

Getty Images

Perhaps cherry picking can work to a certain degree if you limit your interactions to the virtual world, constantly going in and out of oxygen lounges or wellness retreats. Basically, a controlled environment- the bare survival mode. But what happens when that level of control meets an environment that resists control? What do we say to the invisible architects of modern life- the polar researchers, the steel workers and coal miners?

Is anti-ageing then an unattainable utopia?

Adaptation vs. Optimisation

There is no denying that India is experiencing the worst air quality in its history. With dynamic cities like Mumbai and Delhi are forever expanding, I believe resilience is second nature.

Wellness isn’t about engineering an ideal existence in India although we are a bunch that are little obsessed with futurism; its about moderation and knowing when to push forward and when to pause.

Johnson’s post interview tweet on the X, analogized the problem of normalizing poor air quality in India to America’s fight with obesity. While these are examples of desensitization and air pollution is certainly an undeniably serious issue in India, is Johnson’s approach -one that heavily relies on hyper-controlled conditions the only road ahead?

The reality is that in everyday life, complete avoidance is neither practical nor possible. You can’t simply move from oxygen lounges to “blue zones”. Nor can you accept bare survival as the norm! The challenges lie in navigating the uncontrolled variables of life without retreating from them.

Johnson’s exit from India this week is representation of the cutting edge of human optimization- where science, health, tech and luxury intersect. But at the heart of our obsession with longevity, perhaps we should reconsider how effectively you and I can adapt to the world around us.

Next Story